12/28/2023 0 Comments Stem inc 2017![]() It was originally released by the China Society for Cell Biology on 9 January 2021. This standard specifies the technical requirements, test methods, test regulations, instructions for use, labelling requirements, packaging requirements, storage requirements, transportation requirements and waste disposal requirements for hMSC, which is applicable to the quality control for hMSC. 'Human Mesenchymal Stem Cells' is the latest set of guidelines on hMSC in China, jointly drafted and agreed upon by experts from the Chinese Society for Stem Cell Research. Therefore, there is an urgent need for consensus standard for the quality control and technical specifications of MSCs. However, heterogeneity of MSCs has become a prominent obstacle to limit their translation into practice, as cells from different tissue sources or each individual have great differences in their transcriptomic signatures, differentiation potential and biological functions. Mesenchymal stem cells (MSCs) have attracted great interest for cell therapy and tissue regeneration due to their self-renewal capacity, multipotency and potent immunomodulatory effects on immune cells. 17 Beijing Technology and Business University, Beijing, China.16 China Medicinal Biotech Association, Beijing, China.15 Nuwacell Biotechnology Co., Ltd, Hefei City, China.14 Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.13 Department of Cardiovascular Surgery of the First Affiliated Hospital & Institute for Cardiovascular Science, Collaborative Innovation Center of Hematology, State Key Laboratory of Radiation Medicine and Protection, Medical College, Soochow University, Suzhou, China.12 China National GeneBank, Shenzhen, China.10 Zephyrm Biotechnologies Co., Ltd, Beijing, China.9 National Institutes for Food and Drug Control, Beijing, China.8 Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China.7 Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China.6 China National Institute of Metrology, Beijing, China.5 Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, China.4 University of Chinese Academy of Sciences, Beijing, China.3 National Stem Cell Resource Center, State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China.2 Chinese Society for Stem Cell Research, Shanghai, China.1 Center for Stem Cell Biology and Tissue Engineering, Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Sun Yat-Sen University, Guangzhou, China.
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